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HelpTest Code STRC Standard Renal Clearance, Plasma and Random Urine
Specimen Required
Contact MLI for approval prior to ordering this test.
Both plasma and urine are required.
Specimen Type: Plasma
Container/Tube: 6-mL Green top (sodium heparin)
Specimen Volume: 3-4 mL
Collection Instructions: Label specimen as plasma.
Specimen Type: Urine
Container/Tube: Sarstedt 5 mL Aliquot Tube (T914)
Specimen Volume: 5 mL
Collection Instructions:
1. Collect a random urine collection.
2. No preservative.
3. Label specimen as urine.
Useful For
Precise measurement of glomerular filtration rate and renal plasma flow
Profile Information
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| IOTC | Iothalamate Clearance | No | Yes |
| PAHCC | PAH Clearance | No | Yes |
Method Name
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
Reporting Name
Standard Renal ClearanceSpecimen Type
Plasma Na HeparinUrine
Specimen Minimum Volume
2 mL plasma/5 mL urine
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Plasma Na Heparin | Refrigerated (preferred) | 7 days | |
| Frozen | 7 days | ||
| Urine | Refrigerated (preferred) | 7 days | |
| Frozen | 7 days |
Reject Due To
| All specimens will be evaluated at Mayo Clinic Laboratories for test suitability. |
Reference Values
GLOMERULAR FILTRATION RATE
20 years: 87-141 mL/min/SA
(Iothalmate) Decreases by 4.95 mL/min/decade
≤ 19 years: Not established
20 years: 87-141
21 years: 86-140
22 years: 86-140
23 years: 85-139
24 years: 85-139
25 years: 84-138
26 years: 84-138
27 years: 83-137
28 years: 83-137
29 years: 82-136
30 years: 81-136
31 years: 81-136
32 years: 81-135
33 years: 80-135
34 years: 80-134
35 years: 79-134
36 years: 79-133
37 years: 78-133
38 years: 78-132
39 years: 77-132
40 years: 77-131
41 years: 76-131
42 years: 76-130
43 years: 75-130
44 years: 75-129
45 years: 74-129
46 years: 74-128
47 years: 73-128
48 years: 73-127
49 years: 72-127
50 years: 72-126
51 years: 72-126
52 years: 71-125
53 years: 71-125
54 years: 70-124
55 years: 70-124
56 years: 69-123
57 years: 69-123
58 years: 68-122
59 years: 68-122
60 years: 67-121
61 years: 67-121
62 years: 66-120
63 years: 66-120
64 years: 65-119
65 years: 65-119
66 years: 65-119
67 years: 64-118
68 years: 64-118
69 years: 63-117
70-150 years: 62-116
PARA-AMINOHIPPURATE (PAH) CLEARANCE
PAH Clearance
0-19 years: not established
20-29 years: >448 mL/min/SA
30-39 years: >413 mL/min/SA
40-49 years: >378 mL/min/SA
50-59 years: >343 mL/min/SA
60-69 years: >308 mL/min/SA
70-79 years: >273 mL/min/SA
80-89 years: >238 mL/min/SA
90-99 years: >203 mL/min/SA
Note: Reference range decreases by 35mL/decade.
FILTRATION FRACTION
>or=16 years: 18-22%
Day(s) Performed
Monday through Friday
Report Available
Same day/1 to 4 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
82542 x 7
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| STRC | Standard Renal Clearance | 96403-1 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| IOTC | Iothalamate Clearance | 90995-2 |
| PAHC | PAH Clearance | 96404-9 |
| FILT | Filtration Fraction | 96405-6 |
| CMT13 | Comment | 77202-0 |