Test Code LAB66 Creatinine
Additional Codes
CPT Code: 82565
Methodology
This battery is also included in Basic Metabolic Panel (LAB15); Comprehensive Metabolic Panel (LAB17); Creatinine Clearance, Plasma or Serum and Urine (LAB818); and Renal Function Panel (LAB19).
Performing Laboratory
TidalHealth Peninsula Regional - Core Laboratory: Chemistry
Specimen Requirements
Submit only 1 of the following specimens:
Plasma
Draw blood in a green-top (lithium heparin) tube. Spin down and send 2 mL of lithium heparin plasma. Hemolyzed specimen is not acceptable.
Note: 1. Indicate plasma.
2. Label specimen appropriately (plasma).
Serum
Draw blood in a gold-top serum gel tube. Spin down and send 2 mL of serum. Hemolyzed specimen is not acceptable.
Note: 1. Indicate serum.
2. Label specimen appropriately (serum).
Reference Values
Creatinine
Males
0-11 months: 0.30-1.00 mg/dL
12 months-11 years: 0.30-0.70 mg/dL
12-17 years: 0.50-1.00 mg/dL
≥18 years: 0.64-1.27 mg/dL
Females
0-11 months: 0.30-1.00 mg/dL
12 months-11 years: 0.30-0.70 mg/dL
12-17 years: 0.50-1.00 mg/dL
≥ 18 years: 0.44-1.03 mg/dL
Note: Serum acetoacetate will lower creatinine results. Acetone and α-ketobutyric acid will elevate results.
Estimated Glomerular Filtration Rate (eGFR) by CKD-EPI Equation
eGFR Reference Range: ≥60 mL/min/1.73 m2
When calculating eGFR, the equation takes into account the patient’s serum creatinine, age, sex, and race. African-American and non-African American eGFR values will be reported from the eGFR calculation.
eGFR will not be reported for patients <18 years of age. eGFR by this equation has been shown to be valid for diabetic patients but not for pregnant patients. It is not recommended using this for drug dosing - for drug dosing use the CG equation.
According to the Kidney Disease: Improving Global Outcomes (KDIGO) CKD work group, chronic kidney disease (CKD) is defined as the abnormalities of kidney structure or function, present for more than 3 months, with implications for health. CKD should be classified by cause, GFR category, and albuminuria category.
KDIGO guidelines provide the following GFR categories:
Stage |
Terms |
GFR mL/min/1.73 m |
G1* |
Normal or high |
90 |
G2* |
Mildly decreased |
60 to 89 |
G3a |
Mildly to moderately decreased |
45 to 59 |
G3b |
Moderately to severely decreased |
30-44 |
G4 |
Severely decreased |
15-29 |
G5 |
Kidney failure |
<15 |
*In the absence of evidence of kidney damage, neither G1 nor G2 fulfill criteria for CKD.
Clinical Reference
Kidney Disease: Improving Global Outcomes (KDIGO) CKD Work Group. KDIGO 2012 clinical practice guideline for the evaluation and management of chronic kidney disease. Kidney Int Suppl 2013;3:1-150
KDOQI US Commentary on the 2012 KDIGO Clinical Practice Guideline for the Evaluation and Management of CKD. Am J Kidney Dis 2014;63:713-735
Additional Information
Available STAT