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Test Code LAB36 TOBRAMYCIN PEAK

Additional Codes

CPT Code: 80200

Performing Laboratory

Peninsula Regional Medical Center - Chemistry

Specimen Requirements

Submit only 1 of the following specimens:

 

Plasma

Draw blood in a green-top (lithium heparin) tube. (Hemolyzed specimen is not acceptable.) Spin down and send 2 mL of lithium heparin plasma. Plasma for a peak level should be drawn 30 minutes after completion of a 30 minute infusion or within 15 minutes after completion of a 60 minute infusion of an intravenous dose or 60 minutes after an intramuscular or oral dose of tobramycin.

Note: 1. Indicate plasma.

2. Label specimen appropriately (plasma).

 

Serum

Draw blood in a gold-top serum gel tube. (Hemolyzed specimen is not acceptable.) Spin down and send 2 mL of serum. Serum for a peak level should be drawn 30 minutes after completion of a 30 minute infusion or within 15 minutes after completion of a 60 minute infusion of an intravenous dose or 60 minutes after an intramuscular or oral dose of tobramycin.

Note: 1. Indicate serum.

2. Label specimen appropriately (serum).

Reference Values

Therapeutic range: 5.0-10.0 mcg/mL

Critical value (automatic call-back): >12.0 mcg/mL

Note: Variable time to peak concentration may be delayed in patients with abnormal renal function or large volume of distribution. Inactivation of aminoglycosides can be caused by high concentration of beta-lactam (eg, penicillin, cephalosporin).