Test Code LAB2570 Dexamethasone Suppression
Additional Codes
CPT Code: 82533
Label Code: DEX SUPP
Performing Laboratory
TidalHealth Peninsula Regional - Core Laboratory: Chemistry
Specimen Requirements
Laboratory Orders
Laboratory orders DEX1 for 0800 the day after dexamethasone administration.
Inpatient Preparation
1. Administer 1 mg of dexamethasone orally and a sedative to patient at 2300.
Note: Laboratory does not supply dexamethasone or sedative.
2. Patient must be fasting throughout procedure.
3. Do not disturb patient’s sleep.
Outpatient and Outreach collection of the morning specimen is permitted. The patient is responsible for taking the medication as prescribed the night before. The collection must be completed between 0800-0900.
Specimen Collection
Submit only 1 of the following specimens:
Plasma
Draw blood in a green-top (lithium heparin) tube at 0800 the morning following dexamethasone and sedative administration. (Hemolyzed specimen is not acceptable.) Spin down, separate within 2 hours of draw, and send 2 mL of lithium heparin plasma.
Note: 1. Indicate plasma.
2. Label specimen appropriately (plasma).
Serum
Draw blood in a gold-top serum gel tube at 0800 the morning following dexamethasone and sedative administration. (Hemolyzed specimen is not acceptable.) Spin down, separate within 2 hours of draw, and send 2 mL of serum.
Note: 1. Indicate serum.
2. Label specimen appropriately (serum).
Reference Values
<5 mcg/dL
Note: Depression, estrogen, phenytoin, and stress may give false-positive results. Twenty-three percent of hospitalized chronically ill patients and 13% of obese patients give false-positive results.