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Test Code LAB000 - Enter Specimen type, Source, and Test Name Diabetes Mellitus Type 1 Evaluation, Serum

Additional Codes

Mayo test code: DBS1

Useful For

Distinguishing type 1 from type 2 diabetes mellitus

 

Identifying individuals at risk of type 1 diabetes (including high-risk relatives of patients with diabetes)

 

Predicting future insulin requirement treatment in patients with adult-onset diabetes

Profile Information

Test ID Reporting Name Available Separately Always Performed
DMEI Diabetes Interpretation, S No Yes
GD65S GAD65 Ab Assay, S Yes Yes
INAB Insulin Abs, S Yes Yes
IA2 IA-2 Ab, S Yes Yes
EZNT8 ZnT8 Ab, S Yes Yes

Method Name

GD65S, INAB, IA2: Radioimmunoassay (RIA)

EZNT8: Enzyme-Linked Immunosorbent Assay (ELISA)

DMEI: Interpretive Comments

Reporting Name

Diabetes Mellitus Type 1 Evaluation

Specimen Type

Serum


Specimen Required


Collection Container/Tube:

Preferred: Red top

Acceptable: Serum gel

Submission Container/Tube: Plastic vial

Specimen Volume: 4 mL

Collection Instructions: Centrifuge and aliquot serum into a plastic vial.


Specimen Minimum Volume

2 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 28 days
  Frozen  28 days
  Ambient  72 hours

Reject Due To

Gross hemolysis Reject
Gross lipemia Reject
Gross icterus Reject

Reference Values

GLUTAMIC ACID DECARBOXYLASE (GAD65) ANTIBODY

≤0.02 nmol/L

Reference values apply to all ages.

 

INSULIN ANTIBODIES

≤0.02 nmol/L

Reference values apply to all ages.

 

ISLET ANTIGEN 2 (IA-2) ANTIBODY

≤0.02 nmol/L

Reference values apply to all ages.

 

ZINC TRANSPORTER 8 (ZnT8) ANTIBODY

< 15.0 U/mL

Reference values apply to all ages.

Day(s) Performed

GAD65 antibody: Monday through Friday

Insulin antibodies: Monday, Wednesday, Friday

IA-2 antibody, Zinc Transporter 8 Antibody: Tuesday, Thursday

Report Available

7 to 10 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

See Individual Test IDs

CPT Code Information

86337

86341 x3

LOINC Code Information

Test ID Test Order Name Order LOINC Value
DBS1 Diabetes Mellitus Type 1 Evaluation 104673-9

 

Result ID Test Result Name Result LOINC Value
81596 GAD65 Ab Assay, S 30347-9
89588 IA-2 Ab, S 81155-4
8666 Insulin Abs, S 60463-7
34268 Diabetes Interpretation, S 69048-7
64926 ZnT8 Ab, S 76651-9