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Test Code LAB000 - Enter Specimen type, Source, and Test Name 11-Deoxycorticosterone, Serum

Additional Codes

Mayo test code: DOCS

Useful For

Diagnosis of suspected 11-hydroxylase deficiency, including the differential diagnosis of 11-beta-hydroxylase 1 (CYP11B1) versus 11-beta-hydroxylase 2 (CYP11B2) deficiency

 

Diagnosis of glucocorticoid-responsive hyperaldosteronism

 

Evaluating congenital adrenal hyperplasia newborn screen-positive children, when elevations of 17-hydroxyprogesterone are only moderate, suggesting possible 11-hydroxylase deficiency

Testing Algorithm

For more information see Steroid Pathways.

Special Instructions

Method Name

Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)

Reporting Name

11-Deoxycorticosterone, S

Specimen Type

Serum


Specimen Required


Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube:

Preferred: Red top

Acceptable: Serum gel

Submission Container/Tube: Plastic vial

Specimen Volume: 0.5 mL

Collection Instructions:

1. Morning (8 a.m.) specimen is preferred.

2. Centrifuge and aliquot serum into a plastic vial.


Specimen Minimum Volume

0.4 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 21 days
  Frozen  21 days
  Ambient  7 days

Reject Due To

Gross hemolysis Reject
Gross lipemia OK
Gross icterus OK

Reference Values

≤18 years: <30 ng/dL

>18 years: <10 ng/dL

Day(s) Performed

Tuesday

Report Available

3 to 10 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

82633

LOINC Code Information

Test ID Test Order Name Order LOINC Value
DOCS 11-Deoxycorticosterone, S 1656-8

 

Result ID Test Result Name Result LOINC Value
46922 11-Deoxycorticosterone, S 1656-8