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Secretin Stimulation Test

Important Note

To schedule, the ordering providers office calls ORU directly at 410-677-6601. 

  • Epic providers should use the activity Prep for Case to place the order. 
  • Non-Epic providers must fax a copy of the order to ORU.  The order must include:
    • patient full name and date of birth
    • ICD code
    • the test name
    • patient weight
    • med to be administered (Secretin) and dose
    • the order must be signed and dated by the ordering clinician

Patient preparation

Patient must be fasting (no food or drink) for 12 hours prior to the test.

  • Patient must not smoke for at least 2 hours prior to the test.

For 12 hours before this test do not take multivitamins or dietary supplements containing biotin (vitamin B7).

 

For 5 days before the test, stop taking

  • Prilosec
  • Protonix
  • Nexium,
  • Prevacid
  • Aciphex.

You may use the following medications up to 24 hours before the test: 

  • Antacids (Maalox, Rolaids, Tums)
  • Pepcid
  • Zantac
  • Axid

The test will take approximately 1 1/2 hours.

 

Specimen Requirements

IV's will be placed in both arms. 

  • Secretin medicine will be given through one IV
  • Blood samples  for Gastrin levels will be drawn from the other IV line at
    • 0 minutes (baseline, before Secretin is administered)
    • 2 minutes post secretin
    • 5 minutes post secretin
    • 10 minutes post secretin
    • 15 minutes post secretin

Performing Laboratory

Mayo Medical Laboratories, Rochester, MN